Center for PFAS Research

• Binding of Per- and Polyfluoroalkyl Substances to the Human Pregnane X Receptor

  Published on November 23, 2020
  The human pregnane X receptor is found to be a host for PFAS that lead to its overactivation.

• PFAS and Dissolved Organic Carbon Enrichment in Surface Water Foams on a Northern U.S. Freshwater Lake

  Published on November 8, 2020
  This study examines the concentration of per- and polyfluoroalkyl substances (PFAS) in foams on surface waters impacted by aqueous film-forming foam.

• Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science and a Proposed Path Forward

  Published on September 8, 2020
  We summarize currently available information relevant to problem formulation/prioritization, exposure, and hazard/effects of PFAS in the context of regulatory and ecological risk assessment activities from around the world

• Electrochemical Destruction of 'Forever Chemicals': The Right Solution at the Right Time

  Published on June 1, 2020
  One promising remediation method for PFAS is electrochemical oxidation.

• Emerging Contaminants: The Latest Research on PFAS

  Published on November 13, 2019
  This webinar features the latest research on PFAS including impacts on reproductive and child health, the biological effects of exposure on fish and wildlife populations and more.

• Scientific Evidence and Recommendations for Managing PFAS Contamination in Michigan

  Published on December 7, 2018
  This report, written by the Michigan PFAS Science Advisory Panel, compiles research and recommendations for managing PFAS contamination in Michigan.

• Spatial and temporal trends of poly- and perfluoroalkyl substances in fish fillets and water collected from pool 2 of the Upper Mississippi River

  Published on August 14, 2017
  Overall, between 2009 and 2013, PFOS concentrations decreased by 65, 76, and 50% for bluegill, freshwater drum, and white bass.

• Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Drinking Water Linked to Industrial Sites, Military Fire Training Areas, and Wastewater Treatment Plants

  Published on August 9, 2016
  This article presents a spatial analysis of 2013–2015 national drinking water PFAS concentrations from the U.S. Environmental Protection Agency’s (US EPA) third Unregulated Contaminant Monitoring Rule (UCMR3) program.

• Chemopreventive Agents Attenuate Rapid Inhibition of Gap Junctional Intercellular Communication Induced by Environmental Toxicants

  Published on June 7, 2016
  Our data demonstrate that in vitro evaluation of gap junctional intercellular communication can be used as an effective screening tool for identification of chemicals with potential chemopreventive activity.

• Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model

  Published on May 29, 2015
  Accurate assessments of risk posed by toxic agents, and the role of dietary phytochemicals play in preventing or reversing the effects of these agents must take into account the specific mechanisms involved in the cancer process.