Center for PFAS Research

• Inhibition of Gap Junctional Intercellular Communication by Perfluorinated Compounds in Rat Liver and Dolphin Kidney Epithelial Cell Lines in Vitro and Sprague-Dawley Rats in Vivo

  Published on August 1, 2002
  The effects of PFOS and related sulfonated fluorochemicals on gap junctional intercellular communication (GJIC) were studied using a rat liver epithelial cell line and a dolphin kidney epithelial cell line.

• Inhibition of gap junctional intercellular communication by perfluorinated fatty acids is dependent on the chain length of the fluorinated tail

  Published on January 6, 1999
  This study indicates that the determining factor of gap junctional intercellular communication (GJIC) inhibition was probably the fluorinated tail of PFFAs.

• Embryonic exposures to perfluorooctanesulfonic acid (PFOS) disrupt pancreatic organogenesis in the zebrafish, Danio rerio

  Perfluorooctanesulfonic acid (PFOS) is a ubiquitous environmental contaminant, previously utilized as a non-stick application for consumer products and firefighting foam.

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